Evaluación diagnóstica y manejo terapéutico farmacológico en pacientes con fibrilación auricular

Autores/as

  • Orlando Robert Sequeira Universidad Nacional de Asunción. Hospital de Clínicas, División de Medicina Cardiovascular. San Lorenzo. Paraguay
  • Judith María Torales Universidad Nacional de Asunción. Hospital de Clínicas, División de Medicina Cardiovascular. San Lorenzo. Paraguay
  • Laura Beatriz García 1. Universidad Nacional de Asunción. Hospital de Clínicas, División de Medicina Cardiovascular. San Lorenzo. Paraguay. 2. Sanatorio Metropolitano. Departamento de Investigación en Ciencias de la Salud. Fernando de la Mora. Paraguay
  • Osmar Antonio Centurión 1. Universidad Nacional de Asunción. Hospital de Clínicas, División de Medicina Cardiovascular. San Lorenzo. Paraguay 2. Sanatorio Metropolitano. Departamento de Investigación en Ciencias de la Salud. Fernando de la Mora. Paraguay

DOI:

https://doi.org/10.18004/mem.iics/1812-9528/2019.017.02.86-101

Palabras clave:

Fibrilación Auricular, tratamiento farmacológico, agentes anti-arrítmicos

Resumen

La fibrilación auricular (FA) es la arritmia sostenida más frecuente que puede presentarse en una amplia variedad de condiciones clínicas. A pesar de los progresos en el tratamiento de los pacientes con FA, esta arritmia sigue siendo una de las más importantes causas de accidente cerebrovascular, insuficiencia cardiaca, muerte súbita y morbilidad cardiovascular en todo el mundo. El objetivo del tratamiento con fármacos antiarrítmicos es mejorar los síntomas relacionados con la FA, y buscar un equilibrio entre la carga sintomática, la posibilidad de reacciones farmacológicas adversas y las preferencias del paciente. El control de la frecuencia cardiaca a corto y largo plazo se puede lograr con bloqueadores beta, digoxina, bloqueadores de los canales del calcio o tratamiento combinado. Si bien otros fármacos antiarrítmicos de clase III también tienen un efecto limitador de la frecuencia, solo deben emplearse para el control del ritmo cardiaco. Restaurar y mantener el ritmo sinusal también es una parte integral del tratamiento de la FA. Los fármacos antiarrítmicos de clase III duplican la tasa de pacientes en ritmo sinusal. El tratamiento para el control del ritmo está indicado para mejorar los síntomas de los pacientes con FA que siguen sintomáticos a pesar del tratamiento adecuado para el control de la frecuencia cardiaca. La combinación de antiarrítmicos que prolongan el intervalo QT no se debe emplear para el control del ritmo cardiaco en la FA.

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Centurión OA, Aquino NJ, García LB, Torales JM. Idarucizumab humanized monoclonal antibody fragment, for reversal of Dabigatran therapy for atrial fibrillation. Blood Heart Circ. 2017;1:DOI:10.15761/BHC:1000105.

Lopes R, Rordorf R, De Ferrari G, Leonardi S, Thomas L, Wojdyla D, et al. Digoxina y mortalidad en la fibrilación auricular. J Am Coll Cardiol 2018;71:1063-74.

Nguyen TN, Hilmer SN, Cumming RG. Review of epidemiology and management of atrial fibrillation in developing countries. Int J Cardiol. 2013;167:2412-20.

Oldgren J, Healey JS, Ezekowitz M, Commerford P, Avezum A, Pais P, et al. RE-LY Atrial Fibrillation Registry Investigators. Variations in cause and management of atrial fibrillation in a prospective registry of 15,400 emergency department patients in

countries: the RE-LY Atrial Fibrillation Registry. Circulation. 2014;129:1568-76.

Chiang CE, Naditch-Brule L, Murin J, Goethals M, Inoue H, O‟Neill J, et al. Distribution and risk profile of paroxysmal, persistent, and permanent atrial fibrillation in routine clinical practice: insight from the real-life global survey evaluating patients with atrial fibrillation international registry. Circ Arrhythm Electrophysiol. 2012;5:632-39.

Guerra F, Brambatti M, Nieuwlaat R, Marcucci M, Dudink E, Crijns HJGM, et al. Symptomatic atrial fibrillation and risk of cardiovascular events: data from the Euro Heart Survey. Europace. 2017;19(12):1922-29.

Kirchhof P et al. Grupo de Trabajo de la Sociedad Europea de Cardiología (ESC) para el diagnóstico y tratamiento de la fibrilación auricular. Rev Esp Cardiol 2017; 70(1):50.e1-e84.

Ziff OJ, Lane DA, Samra M, Griffith M, Kirchhof P, Lip GY, et al. Safety and efficacy of digoxin: systematic review and meta-analysis of observational and controlled trial data. BMJ. 2015;351:h4451.

Khand AU, Rankin AC, Martin W, Taylor J, Gemmell I, Cleland JG. Carvedilol alone or in combination with digoxin for the management of atrial fibrillation in patients with heart failure? J Am Coll Cardiol. 2003; 42:1944–51.

Van Gelder IC, Groenveld HF, Crijns HJ, Tuininga YS, Tijssen JG, Alings AM, et al. Lenient versus strict rate control in patients with atrial fibrillation. N Engl J Med. 2010;362:1363–73.

Groenveld HF, Crijns HJ, Van den Berg MP, Van Sonderen E, Alings AM, Tijssen JG, et al. The effect of rate control on quality of life in patients with permanent atrial fibrillation: data from the RACE II (Rate Control Efficacy in Permanent Atrial Fibrillation II) study. J Am Coll Cardiol. 2011;58:1795–803.

Zi OJ, Kotecha D. Digoxin: the good and the bad. Trends Cardiovasc Med 2016;26: 585–95.

Carlsson J, Miketic S, Windeler J, Cuneo A, Haun S, Micus S, et al. Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) study. J Am Coll Cardiol. 21 de mayo de 2003;41(10):1690-6.

Centurión OA, Shimizu A. Rate Control Strategy Elevated To Primary Treatment For Atrial Fibrillation: Has The Last Word Already Been Spoken? J Atr Fibrillation 2015;7(4):50-6

Centurión OA. Atrial fibrillation in the Wolff-Parkinson-White syndrome. J Atr Fibrillation 2011;4(1): 287.

Centurión OA, Torales JM, García LB. Sudden Cardiac Death Associated to Auriculoventricular Accessory Pathways: Sleeping with the Enemy. EC Cardiology 2018; 5(9):612-15.

Centurión OA, Shimizu A, Isomoto S, Konoe A. Mechanisms for the genesis of paroxysmal atrial fibrillation in the Wolff-Parkinson-White syndrome: Intrinsic atrial muscle vulnerability vs. electrophysiological properties of the accessory pathway. Europace 2008;10(3): 294-302.

Wellens HJJ and Durrer D. Wolff-Parkinson-White syndrome and atrial fibrillation. Relation between refractory period of the accessory pathway and ventricular rate during atrial fibrillation. Am J Cardiol 1974;34(7):772-82.

Waspe LE, Brodman R, Kim SG, Fisher JD. Susceptibility to atrial fibrillation and ventricular tachyarrhythmia in the Wolff-Parkinson-White syndrome: Role of the accessory pathway. Am Heart J 1986;112(6):1141-52.

Centurión OA, Scavenius KE, García LB, Miño L, Torales J, Sequeira O. Atrioventricular Nodal Catheter Ablation in Atrial Fibrillation Complicating Congestive Heart Failure. J Atr Fibrillation. 2018 Jun 30;11(1):1813. doi: 10.4022/jafib.1813.

Palmisano P, Aspromonte V, Ammendola E, Dell‟era G, Ziacchi M, Guerra F, et al. Effect of fixed-rate vs. rate-RESPONSIve pacing on exercise capacity in patients with permanent, refractory atrial fibrillation and left ventricular dysfunction treated with atrioventricular junction aBLation and bivEntricular pacing (RESPONSIBLE): a prospective, multicentre, randomized, single-blind study. Europace. 2017;19 (3):414-20.

Ringwala S, Knight BP, Verma N. Permanent His bundle pacing at the time of atrioventricular node ablation: A 3-dimensional mapping approach. HeartRhythm Case Rep. 2017;3 (6):323-325.

Occhetta E, Bortnik M, Magnani A, Francalacci G, Piccinino C, Plebani L, Marino P. Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation: a crossover, blinded, randomized study versus apical right ventricular pacing. J. Am. Coll. Cardiol. 2006;47(10):1938-45.

Huang W, Su L, Wu S, Xu L, Xiao F, Zhou X, et al. Benefits of Permanent His Bundle Pacing Combined With Atrioventricular Node Ablation in Atrial Fibrillation Patients With Heart Failure With Both Preserved and Reduced Left Ventricular Ejection Fraction. J Am Heart Assoc. 2017;6 (4). pii: e005309. doi: 10.1161/JAHA.116.005309.

Björkenheim A, Brandes A, Andersson T, Magnuson A, Edvardsson N, Wandt B, et al. Predictors of hospitalization for heart failure and of all-cause mortality after atrioventricular nodal ablation and right ventricular pacing for atrial fibrillation. Europace. 2014;16 (12):1772-78.

Hohendanner F, Heinzel FR, Blaschke F, Pieske BM, Haverkamp W, Boldt HL, et al.Pathophysiological and therapeutic implications in patients with atrial fibrillation and heart failure. Heart Fail Rev. 2018;23 (1):27-36.

Carson PE, Johnson GR, Dunkman WB, Fletcher RD, Farrell L, Cohn JN. The influence of atrial fibrillation on prognosis in mild to moderate heart failure. The V-HeFT Studies. The V-HeFT VA Cooperative Studies Group. Circulation. 1993;87 (6 Suppl):VI102-110.

Modin D, Sengeløv M, Jørgensen PG, Bruun NE, Olsen FJ, Dons M, et al. Global longitudinal strain corrected by RR interval is a superior predictor of all-cause mortality in patients with systolic heart failure and atrial fibrillation. ESC Heart Fail. 2018;5 (2):311-18.

Birnie D, Hudnall H, Lemke B, Aonuma K, Lee KL, Gasparini M, et al. Continuous optimization of cardiac resynchronization therapy reduces atrial fibrillation in heart failure patients: Results of the Adaptive Cardiac Resynchronization Therapy Trial. Heart Rhythm. 2017;14 (12):1820-25.

Centurión OA. Atrial Fibrillation Complicating Congestive Heart Failure: Electrophysiological Aspects And Its Deleterious Effect On Cardiac Resynchronization Therapy. J Atr Fibrillation. 2009;2(1):143. doi: 10.4022/jafib.143.

Krijthe BP, Kunst A, Benjamin EJ, Lip GY, Franco OH, Hofman A, et al. Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060. Eur Heart J. 2013;34:2746-51.

Zoni-Berisso M, Lercari F, Carazza T, Domenicucci S. Epidemiology of atrial fibrillation: European perspective. Clin Epidemiol. 2014;6:213-20.

Bjorck S, Palaszewski B, Friberg L, Bergfeldt L. Atrial fibrillation, stroke risk, and warfarin therapy revisited: a population-based study. Stroke. 2013;44:3103-08.

Haim M, Hoshen M, Reges O, Rabi Y, Balicer R, Leibowitz M. Prospective national study of the prevalence, incidence, management and outcome of a large contemporary cohort of patients with incident non-valvular atrial fibrillation. J Am Heart Assoc. 2015;4:e001486.

McManus DD, Rienstra M, Benjamin EJ. An update on the prognosis of patients with atrial fibrillation. Circulation. 2012;126:143-46.

Pant R, Patel M, Garcia-Sayan E, Wassouf M, D‟Silva O, Kehoe RF, et al. Impact of B-type natriuretic peptide level on the risk of left atrial appendage thrombus in patients with nonvalvular atrial fibrillation: a prospective study. Cardiovascular Ultrasound 2016; 14: 4 DOI 10.1186/s12947-016-0047-6.

Ball J, Carrington MJ, McMurray JJ, Stewart S. Atrial fibrillation: profile and burden of an evolving epidemic in the 21st century. Int J Cardiol. 2013;167:1807-24.

Chugh SS, Havmoeller R, Narayanan K, Singh D, Rienstra M, Benjamin EJ, et al. Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study. Circulation. 2014;129:837-47.

Colilla S, Crow A, Petkun W, Singer DE, Simon T, Liu X. Estimates of current and future incidence and prevalence of atrial fibrillation in the U.S. adult population. Am J Cardiol. 2013;112:1142-47.

Heeringa J, van der Kuip DA, Hofman A, Kors JA, van Herpen G, Stricker BH, et al. Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J. 2006;27:949-53.

Lloyd-Jones DM, Wang TJ, Leip EP, Larson MG, Levy D, Vasan RS, et al. Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation. 2004;110:1042-46.

Go AS, Hylek EM, Phillips KA, Chang Y, Henault LE, Selby JV, et al.Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA. 2001;285:2370-75.

Wyse DG, Waldo AL, DiMarco JP, Domanski MJ, Rosenberg Y, Schron EB, et al. A comparison of rate control and rhythm control in patients with atrial fibrillation. The atrial fibrillation follow-up investigation of rhythm management (AFFIRM) investigators. N Engl J Med 2002;347:1825-33.

Van Gelder IC, Hagens VE, Bosker HA, Kingma JH, Kamp O, Kingma T, et al. A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation. N Engl J Med 2002;347:1834.

Opolski G, Torbicki A, Kosior D, Szulc M, Zawadzka M, Pierścińska M,et al. Rhythm control versus rate control in patients with persistent atrial fibrillation. Results of the HOT CAFE Polish Study. Kardiol Pol 2003;59(7):1-16.

Honloser SH, Kuck KH, Lilienthal J. Rhythm or rate control in atrial fibrillation- Pharmacological intervention in atrial fibrillation (PIAF). A randomized trial. Lancet 2000;356:1789-94.

Habibollahi P, Jam SH, Vahdati SS, Baghi HM, Amiri H. Amiodarone in atrial fibrillation: post coronary artery bypass graft. World J Emerg Med 2016;7(4):250-54.

Naccarelli GV, Wolbrette DL, Dell'Orfano JT, Patel HM, Luck JC. Amiodarone: What Have We Learned from Clinical Trials? Clin. Cardiol. 2000;23:73-82.

Zipes DP, Prystowsky EN, Heger JJ. Amiodarone: Electrophysiologic Actions, Pharmacokinetics and Clinical Effects. J Am Coll Cardiol 1984;3(4):1059-71.

Wolbrette D, Gonzalez M, Samii S, Banchs J, Penny-Peterson E, Naccarelli G. Dronedarone for the treatment of atrial fibrillation and atrial flutter: approval and efficacy. Vasc Health Risk Manag 2010;6:517-23.

Reiffel JA. Dronedarone: Where Does it Fit in the AF Therapeutic Armamentarium?

J Atr Fibrillation 2013;5(6):157-63.

Naccarelli GV, Kowey PR. The Role of Dronedarone in the Treatment of Atrial Fibrillation/Flutter in the Aftermath of PALLAS. Curr Cardiol Rev 2014;10:303-8.

Andrikopoulos GK, Pastromas S, Tzeis S. Flecainide: Current status and perspectives in arrhythmia management. World J Cardiol 2015;7(2):76-85.

Aliot E, Capucci A, Crijns HJ, Goette A, Tamargo J. Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation. Europace 2011;13:161-73.

Juan Tamargo J, Le Heuzey JY, Mabo P. Narrow therapeutic index drugs: a clinical pharmacological consideration to flecainide. Eur J Clin Pharmacol 2015;71:549-67.

Camm AJ, Savelieva I. Some patients with paroxysmal atrial fibrillation should carry flecainide or propafenone to self treat. BMJ 2007:334:637. doi: 10.1136/bmj.39143.720602.BE

Khairy P, Nattel S. New insights into the mechanisms and management of atrial fibrillation. Can Med Assoc J 2002;167(9):1012-20.

Lip GYH, Apostolakis S. Atrial fibrillation (acute onset). Clinical Evidence 2014;11:210-253.

O„Neal Humpries J. Unexpected Instant Death Following Successful Coronary Artery Bypass Graft Surgery (and Other Clinical Settings): Atrial Fibrillation, Quinidine, Procainamide, et cetera, and Instant Death. Clin. Cardiol. 1998;21:711-18.

Burashnikov A, Antzelevitch C. New Pharmacological Strategies for the Treatment of Atrial Fibrillation. Ann Noninvasive Electrocardiol. 2009;14(3):290-300.

Mackstaller LL, Alpert J. Atrial Fibrillation: A Review of Mechanism, Etiology, and Therapy. Clin. Cardiol. 1997;20:640-50.

Batul SA, Gopinathannair R. Intravenous Sotalol - Reintroducing a Forgotten Agent to The Electrophysiology Therapeutic Arsenal. J Atr Fibrillation 2017;9(5):1-5.

Chaki AL, Caines AE, Miller AB. Sotalol as Adjunctive Therapy to Implantable Cardioverter-Defibrillators in Heart Failure Patients. Congest Heart Fail. 2009;15:144-47.

Marcus FI. Risks of Initiating Therapy With Sotalol for Treatment of Atrial Fibrillation. J Am Coll Cardiol 1998;32(1):177-80.

Pedersen OD, Brendorp B, Køber L, Torp-Pedersen C. Prevalence, Prognostic Significance, and Treatment of Atrial Fibrillation in Congestive Heart Failure With Particular Reference to the DIAMOND-CHF Study. CHF. 2003;9:333-40.

Jaiswal A, Goldbarg S. Dofetilide induced torsade de pointes: Mechanism, risk factors and management strategies. Indian Heart J 2014;66:640-48.

Ellison KE, Stevenson WG, Sweeney MO, Epstein LM, Maisel WH. Management of Arrhythmias in Heart Failure. CHF. 2003;9:91-9.

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Publicado

2019-08-01

Cómo citar

Sequeira, O. R., Torales, J. M., García, L. B., & Centurión, O. A. (2019). Evaluación diagnóstica y manejo terapéutico farmacológico en pacientes con fibrilación auricular. Memorias Del Instituto De Investigaciones En Ciencias De La Salud, 17(2), 86–101. https://doi.org/10.18004/mem.iics/1812-9528/2019.017.02.86-101

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