Secuelas cognitivas en pacientes con COVID-19 grave: evidencia preliminar desde Paraguay
Palavras-chave:
Deterioro cognitivo, atención, memoria, fluidez verbal, COVID-19 graveResumo
Este estudo preliminar analisou as alterações cognitivas em pacientes que se recuperaram da COVID-19 grave, comparando-os com pacientes que apresentaram formas leves da doença. Foram avaliados a memória diferida, a atenção, a fluência verbal e o desempenho cognitivo global por meio do Montreal Cognitive Assessment (MoCA), aplicado após a recuperação clínica. A amostra incluiu 20 adultos residentes em Ciudad del Este, no Paraguai, distribuídos em dois grupos de acordo com a gravidade clínica. Os pacientes com COVID-19 grave apresentaram pontuações mais baixas na memória diferida do que aqueles com COVID-19 leve (3,1 ± 1,7 vs. 4,7 ± 0,7; p = 0,002), menor fluência verbal (1,7 ± 0,8 vs. 2,4 ± 0,5; p = 0,002) e menor pontuação total no MoCA (20,5 ± 2,3 vs. 25,9 ± 1,9; p < 0,001). As diferenças na atenção não alcançaram significância estatística (p = 0,11). Esses achados fornecem evidências preliminares sobre possíveis sequelas cognitivas persistentes após a COVID-19 grave e reforçam a necessidade de acompanhamento neurocognitivo. Recomenda-se a realização de estudos longitudinais com amostras mais amplas e análises ajustadas por idade, comorbidades, nível de escolaridade e duração da internação.
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Copyright (c) 2026 Eliana M. Jara Casco, Edgar Fernando Gamarra Silva, Ronaldo L. Rodas Jara, Liza R. Rodas Jara, Diana Báez Delvalle, María Isabel Rodríguez- Riveros, Julio Torales
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
