Identification of Clinical Factors Related to Greater Mortality Associated with Acute Renal Failure in Intensive Care Patients

Authors

  • José María Gamarra Ortíz Universidad Nacional del Este, Facultad de Ciencias de la Salud, Hospital Regional de Ciudad del Este. Departamento de Cardiología, Cátedra de Clínica Médica II. Ciudad del Este. Paraguay. https://orcid.org/0009-0000-7488-0993
  • Osmar Antonio Centurión Sanatorio Metropolitano, Departamento de Investigación en Ciencias de la Salud. Fernando de la Mora. Paraguay. Universidad Nacional de Asunción, Hospital de Clínicas, División de Medicina Cardiovascular. San Lorenzo, Paraguay. https://orcid.org/0000-0002-6903-6250

DOI:

https://doi.org/10.18004/mem.iics/1812-9528/2024.e22122401

Keywords:

acute renal failure, acute kidney injury, mortality, intensive care unit, Paraguay

Abstract

Acute renal failure (ARF) is one of the most frequent complications in hospitalized patients and is a risk factor for mortality. It is extremely important to identify the association of clinical factors that worsen mortality in patients with ARF admitted to an intensive care unit (ICU). A total of 218 patients were included, of which 63.7% (n=139) were men with a mean age of 43±19 years. The correlation analysis of control, dependent, and independent variables was done through Spearman's coefficient and the OR was analyzed through logistic regression. Of the 218 patients, 33% (n=72) died in the ICU. ARF occurred in 28.4% (n=62) of all patients and of these, 61.3% (n=38) died, with an OR of 4.94 (p 0.0001). The highest proportion of deceased patients were in the AKIN 3 category. The clinical variables of mechanical ventilation (PR 3.57, 95% CI, 0.34-37.93), use of vasoactive drugs (PR 8.32, 95% CI, 3.20-21.64), APACHE III score (PR 1.12, 95% CI, 1.03-1.23), age (PR 1.01, 95% CI, 0.99-1.04) and those who underwent surgery (PR 0.28, 95% CI, 0.10-0.80) had a positive association and increased mortality.

The presence of clinical variables of mechanical ventilation, the use of vasoactive drugs, sepsis, APACHE III stage, age, AKIN 3 category, and a history of surgery before admission to the ICU significantly increase mortality in patients with ARF in ICU.

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Published

2024-01-01

How to Cite

Gamarra Ortíz, J. M., & Centurión, O. A. (2024). Identification of Clinical Factors Related to Greater Mortality Associated with Acute Renal Failure in Intensive Care Patients. Memorias Del Instituto De Investigaciones En Ciencias De La Salud, 22(1). https://doi.org/10.18004/mem.iics/1812-9528/2024.e22122401

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Articulos Originales

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