Predictors of Choledocholithiasis in patients with symptomatic gallstones treated in the II General Surgery Service of Clinica´s Hospital, San Lorenzo, year 2017-2019
Abstract
Symptomatic gallstones can occur associated with lithiasis of the main bile duct, requiring the use of adequate diagnostic tools for subsequent treatment. In this paper, we suggest using the guidelines of the American Society for Gastrointestinal Endoscopy (ASGE), that uses factors such as age, liver tests, and ultrasound findings, categorizing patients as those with low, intermediate, and high probability. of choledocholithiasis. A Retrospective, observational, descriptive, cross-sectional design study, with a non-probabilistic sampling of consecutive cases, on patients with a diagnosis of symptomatic gallstones and suspected stones of the main bile duct admitted to the the 2nd Surgical Department and Service of Clinica´s Hospital of San Lorenzo, between the years 2017 to 2019. With the following results; of a total of 339 patients with the diagnosis of symptomatic gallstones, 6.64% had associated choledocholithiasis. Regarding the very strong predictors of choledocholithiasis, the most frequent (68.6%) was the total bilirubin level ≥ 4mg / dl; 70.6% had a dilated main bile duct as a strong predictor; as a moderate predictor, 84.3% had altered liver enzymes. In conclusion, it was possible to identify that most of the patients presented a high probability of choledocholithiasis and the action taken was to first perform an endoscopic retrograde cholangiography, for therapeutic purposes, and then cholecystectomy, corresponding to the correct management established by current international guidelines.
Downloads
Metrics
References
Almora Carbonell Ceramides Lidia, Arteaga Prado Yanin, Plaza González Tania, Prieto Ferro Yulka, Hernández Hernández Zoraida. Diagnóstico clínico y epidemiológico de la litiasis vesicular. Revisión bibliográfica. Rev Ciencias Médicas [Internet]. 2012 Feb [citado 2021 Mar 03] ; 16( 1 ): 200-214. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-31942012000100021&lng=es.
Quintanilla C, Flisfisch H. Coledocolitiasis. Rev Medicina y Humanidades Vol. 1 N° 3 2009
Jerusalén C, Simón M A. Cálculos biliares y sus complicaciones. Sección 5 Páncreas y vías biliares. Ayudas y prácticas. Asociación Española de Gastroenterología
European Association for the Study of the Liver (EASL). Guías de práctica clínica de la EASL sobre la prevención, diagnóstico y tratamiento de la litiasis biliar. Journal of Hepatology 2016 vol. 65 | 146–181
Buxbaum J., ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis. GASTROINTESTINAL ENDOSCOPY [Internet]. 2019 [Consultado 4 Mar 2021]; Vol 89(6). Disponible en: https://www.asge.org/docs/default-source/guidelines/asge-guideline-on-the-role-of-endoscopy-in-the-evaluation-and-management-of-choledocholithiasis-2019-june-gie.pdf?sfvrsn=6757df52_4.
Maple JT. The role of endoscopy in the evaluation of suspected choledocholithiasis GASTROINTESTINAL ENDOSCOPY Volume 71, No. 1 : 2010
Kuzu UB1, Ödemiş B2, Dişibeyaz S2, Parlak E2, Öztaş E2, Saygılı F2, Yıldız H2, Kaplan M2, Coskun O2, Aksoy A2, Arı D2, Suna N2, Kayaçetin E2 Management of suspected common bile duct stone: diagnostic yield of current guidelines. HPB (Oxford). 2017 Feb;19(2):126-132. doi: 10.1016/j.hpb.2016.11.003. Epub 2016 Nov 30. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/27914763
SCHWARTZ. PRINCIPIOS DE CIRUGÍA Décima edición. McGRAW-HILL INTERAMERICANA EDITORES, S. A.2015
He H1, Tan C1, Wu J1, Dai N1, Hu W1, Zhang Y1, Laine L2, Scheiman J3, Kim JJ4 Accuracy of ASGE high-risk criteria in evaluation of patients with suspected common bile duct stones. Gastrointest Endosc. 2017 Sep;86(3):525-532. doi: 10.1016/j.gie.2017.01.039. Epub 2017 Feb 4. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/28174126
Kamath SU1, Dharap SB2, Kumar V2Scoring system to preoperatively predict choledocholithiasis. Indian J Gastroenterol. 2016 May;35(3):173-8. doi: 10.1007/s12664-016-0655-y. Epub 2016 May 5. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/27146040
TOZATTI, Joana; MELLO, André Luiz Parizi and FRAZON, Orli. Predictor factors for choledocholithiasis. ABCD, arq. bras. cir. dig. [online]. 2015, vol.28, n.2 [cited 2018-05-21], pp.109-112. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202015000200109&lng=en&nrm=iso>. ISSN 0102-6720. http://dx.doi.org/10.1590/s0102-67202015000200006.
Charatcharoenwitthaya P1, Sattawatthamrong Y, Manatsathit S, Tanwandee T, Leelakusolvong S, Kachintorn U, Leungrojanakul P, Boonyapisit S, Pongprasobchai S. Predictive factors for synchronous common bile duct stone in patients with symptomatic cholelithiasis. J Med Assoc Thai. 2004 Feb;87(2):131-6. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/15061295
Jose Bueno Lledó, Jose Luis Ibáñez Cirión, Antonio Torregrosa Gallud, Rafael López Andújar. Design of a preoperative predictive score for choledocholithiasis. Gastroenterol Hepatol 2014;37:511-8 - DOI: 10.1016/j.gastrohep.2014.04.001. disponible en: http://www.elsevier.es/es-revista-gastroenterologia-hepatologia-14-resumen-elaboracion-un-score-predictivo-preoperatorio-S0210570514001381
Singh AN1, Kilambi R2 Single-stage laparoscopic common bile duct exploration and cholecystectomy versus two-stage endoscopic stone extraction followed by laparoscopic cholecystectomy for patients with gallbladder stones with common bile duct stones: systematic review and meta-analysis of randomized trials with trial sequential analysis. Surg Endosc. 2018 Mar 30. doi: 10.1007/s00464-018-6170-8. [Epub ahead of print. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/29603004
Kharbutli B1, Velanovich V.Management of preoperatively suspected choledocholithiasis: a decision analysis. J Gastrointest Surg. 2008 Nov;12(11):1973-80. doi: 10.1007/s11605-008-0624-6. Epub 2008 Aug 6. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/18683008.
Dasari BV1, Tan CJ, Gurusamy KS, Martin DJ, Kirk G, McKie L, Diamond T, Taylor MA. Surgical versus endoscopic treatment of bile duct stones. Cochrane Database Syst Rev. 2013 Dec 12;(12):CD003327. doi: 10.1002/14651858.CD003327.pub4. disponible en: https://www.ncbi.nlm.nih.gov/pubmed/24338858.