Blood pressure patterns in hemodialysis: an observational longitudinal study during interdialytic periods
DOI:
https://doi.org/10.18004/Keywords:
Blood Pressure, Hypertension, Hemodialysis, Chronic Kidney Disease, Long Interdialytic period, Short Interdialytic periodAbstract
Introduction: Arterial hypertension (AH) is highly prevalent among patients with chronic
kidney disease undergoing hemodialysis and is associated with cardiovascular complications.
Blood pressure variability according to the timing of measurement generates diagnostic and
therapeutic uncertainty. Objective: To analyze the behavior of ambulatory blood pressure during
long (72-hour) and short (48-hour) interdialytic periods, relating it to pre- and post-dialysis blood
pressure values and correlating body weight with all blood pressure measurements. Materials
and Methods: Observational, analytical, longitudinal study with repeated measures conducted
in 84 patients undergoing chronic hemodialysis. Home blood pressure measurements (4
determinations per day) were performed over one month during both interdialytic periods.
Paired Student’s t test and Pearson’s correlation coefficient were used. Statistical significance
was set at p<0.05. Results: Systolic blood pressure was higher during the long interdialytic
period compared with the short period (151.12±24.66 vs 139.92±24.69 mmHg; p<0.003).
Diastolic blood pressure was also higher (85.07±13.14 vs 79.40±14.40 mmHg; p<0.008).
A positive correlation was found between weight gain and systolic blood pressure (r=0.43).
Conclusion: Ambulatory blood pressure is significantly higher during the long interdialytic
period. Interdialytic weight gain correlates primarily with systolic blood pressure.
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