Silicosis in Paraguay: the threat is not gone
DOI:
https://doi.org/10.18004/mem.iics/1812-9528/2023.e21142301Keywords:
silicosis, Paraguay, polvo de sílice, enfermedades ocupacionalesAbstract
Occupational diseases remain an unresolved issue in the national medical literature. The most common form of pneumoconiosis is silicosis, which is brought on by inhaling crystalline silica and depending on the susceptibility of the person, the extent of their exposure, and the concentration of the mineral in the air, silicosis can result in different clinical forms. The most prevalent type, chronic silicosis, is linked to a variety of jobs, including well digging and quarry work. In recent times, other trades have been reported that can cause more accelerated forms of the disease in shorter exposure times, worsening worrying outbreaks in working-age adults. With the intention of assessing various elements and highlighting certain clinical and regional demographic aspects, we performed a narrative review of observational studies conducted in Paraguay.
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References
Thomas C, Kelley T . A Brief Review of Silicosis in the United States. Environmental Health Insights 2010:4 21-26. doi: 10.4137/ehi.s4628.
Carnevale F, Rosental P-A, Thoman B. Silica, silicosis and occupational health in the globalized world of the twenty-first century. En: Rosental P-A.ed. Silicosis: A World History. Baltimore: John Hopkins University Press; 2017: 206-33.
Algranti E, Saito CA, Carneiro APS, Bussacos MA. Mortality from silicosis in Brazil: temporal trends in the period 1980-2017. Am J Ind Med. 2021; 64: 178-84. doi: 10.1002/ajim.23215
National Institute for Occupational Safety and Health & Pan American Health Organization. Americas Elimination of Silicosis Initiative. 2010. Acceso: 26/10/22; https://www.paho.org/hq/dmdocuments/2010/Fact%20Sheet%20Silicosis_ilo.pdf
International Agency for Research on Cancer. Silica dust, crystalline, in the form of quartz or cristobalite. En: Arsenic, Metals, Fibres, and Dusts, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Volume 100C. 2012: 355-405. https://www.ncbi.nlm.nih.gov/books/NBK304370/
Fernández-Alvarez R, Martínez-González C, Quero-Martínez Q, Blanco Pérez JJ, Carazo Fernandez L, Prieto Fernández A. Normativa para el diagnóstico y seguimiento de la silicosis. Arch Bronconeumol. 2015; 51(2): 86-93. https://doi.org/10.1016/j.arbres.2014.07.010
Gaviola S, Martin V, Rodríguez E, Sapoznik MM, Contreras A. (Grupo de la Superintendencia de Riesgos del Trabajo de la República Argentina). Guías de actuación y diagnóstico de enfermedades profesionales - 05 Silicosis. 2018. Acceso 26-10-2022. https://www.argentina.gob.ar/sites/default/files/5_guia_de_actuacion_y_diagnostico_-_silicosis_0.pdf
Hoy RF, Jeebhay MF, Cavalin C, Chen W, Cohen RA, Fireman E. Current global perspectives on silicosis-Convergence of old and newly emergent hazards. Respirology. 2022 Jun; 27(6): 387-98. doi: 10.1111/resp.14242
Mazurek J, Attfield M. Silicosis mortality among young adults in the United States, 1968-2004. Am J Ind Med 2008 Aug; 51(8): 568-78. doi: 10.1002/ajim.20597.
Aberkane S. Perceived Health Related Quality of Life Outcomes with Silicosis Patients. Iran J Public Health. 2017 Sep;46(9):1299-300. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632335/
Maás LC. Un estudio sobre la silicosis en nuestro país. Revista de la Facultad de Química y Farmacia 1946; 4: 45.
Mallorquín C, Caballero HR, Balbuena A. Silicosis y silico-tuberculosis. Anales del Sanatorio “Prof Dr Juan Max Boettner” 1963-1964; 3.
Mallorquin C, Mazó D, Caballero R, Serna G, Gómez R, et al. Silicosis: una descripción de 200 casos. Revista Médica del Paraguay 1983; 2: 27-30
Nina A, Bogarín P, Marín P. Silicosis: casos vistos en el Instituto Nacional de Enfermedades Respiratorias y Ambientales. Programa de Residencia en Neumología (Universidad del Norte, Asunción-Paraguay). 2003.
Marín P, Bogarin P, Nina A y Pérez D. Distribución departamental de los casos de silicosis en el Paraguay en los comienzos del siglo XXI. Libro de resúmenes del VII Congreso de Medicina Interna, 2004, Asunción Paraguay. https://www.neumoparaguay.org/files/silicosis_demografia.pdf
Marín P, Bogarin P, Nina A, Pérez D. Silicosis: morbimortalidad intrahospitalaria. Libro de resúmenes del VII Congreso de Medicina Interna, 2004, Asunción Paraguay. https://www.neumoparaguay.org/files/silicosis_morbimortalidad.pdf
Silguero N, Campuzano D, Ojeda M., et al. Silicosis en el Paraguay: estudio observacional. Neumol Cir Tórax, 2015; 74 (2): 158-9. https://www.researchgate.net/publication/319968331_Resumenes_del_VII_Congreso_Paraguayo_de_Neumologia_Luque-Paraguay_noviembre_2014
Cáceres G, Rodríguez P, Chaparro G, Pérez D. Screening de síntomas y espirometria en trabajadores de la Cantera. Trabajo para tesis de posgrado. Programa Residencia Neumología INERAM. https://www.neumoparaguay.org/wp-content/uploads/2022/10/encuesta-en-trabajadores-de-cantera.pdf
Doganay S, Gocmen H, Yikilmaz A, Coskun A. Silicosis due to Denim Sandblasting in Young People: MDCT Findings. Eurasian J Med. 2010 Apr; 42(1): 21-3. doi: 10.5152/eajm.2010.07.
Panchadhyayee P, Saha K, Saha I, Rupam Kumar Ta R, Santanu Ghosh S, Arnab Saha A. Rapidly Fatal Silicosis Among Jewellery Workers Attending a District Medical College of West Bengal, India. Indian J Chest Dis Allied Sci. 2015; 57 (3): 165-71. https://www.researchgate.net/publication/297055979
Hua JT, Zell-Baran L, Go LHT, Kramer MR, Van Bree JB, Chambers D, et al. Demographic, exposure and clinical characteristics in a multinational registry of engineered stone workers with silicosis. Occup Environ Med. 2022; 79(9): 586-93. doi: 10.1136/oemed-2021-108190.
Newbigin K, Parsons R, Deller D, Edwards R, McBean R. Stonemasons with silicosis: Preliminary findings and a warning message from Australia. Respirology. 2019; 24(12): 1220-21. doi: 10.1111/resp.13672
Vanka KS, Shukla S, Gomez HM, James C, Palanisami T, Williams K, et al. Understanding the pathogenesis of occupational coal and silica dust- associated lung disease. Eur Respir Rev 2022; 31: 210250. doi: 10.1183/16000617.0250-2021
Ministerio de Obras Publicas y Comunicaciones- Vice Ministerio de Minas y Energías. Registro Nacional de Canteras. Acceso en agosto 2022. https://www.ssme.gov.py/
Zevaco S. Minería en territorio paraguayo. BASE-IS, Asunción; Fundación Rosa Luxemburgo-Ministerio Federal de Cooperación y Desarrollo de Alemania. Ed: Arandurã. (Diciembre, 2019). 164p. Accesible en: http://www.baseis.org.py/wp-content/uploads/2020/03/2019_Dic-Mineria-en-el-territorio-paraguayo-comprimido_compressed-1.pdf
Austin E, James C, Tessier J. Early detection methods for silicosis in Australia and internationally: a review of the literature. Int J of Environ Res Public Health 2021; 18 (15): 8123. doi: 10.3390/ijerph18158123.
Şener MU, Şimşek C, Özkara Ş Evran H, Bursali I, Gökçek A, et al. Comparison of the International Classification of High-resolution Computed Tomography for occupational and environmental respiratory diseases with the International Labor Organization International Classification of Radiographs of Pneumoconiosis. Ind Health. 2019 Aug 3; 57(4): 495-502. doi: 10.2486/indhealth.2018-0068.
Gowda V, Cheng G, Saito K. The B reader program, silicosis, and physician workload management: a niche for AI technologies,” J Occupl Environ Med 2021; 63(7): e471-e473. Doi: 10.1097/JOM.0000000000002271
Lee J, Shin J, Choi, B. Serum levels of IL-8 and ICAM-1 as biomarkers for progressive massive fibrosis in coal workers’ pneumoconiosis. Korean Med. Sci. 2015; 30: 140-4. doi: 10.3346/jkms.2015.30.2.140
Blanco-Pérez J, Blanco-Dorado S, Rodriguez-Garcia J, Gonzalez-Bello ME, Salgado-Barreira A, Caldera-Díaz AC, et al. Serum levels of inflammatory mediators as prognostic biomarker in silica exposed workers. Sci Rep 2021; 11(1): 13348. doi: 10.1038/s41598-021-92587-0
León-Jiménez A, Hidalgo-Molina A, Conde-Sánchez M, Pérez-Alonso A, Morales-Morales JM, García-Gámez EM. Artificial stone silicosis: rapid progression following exposure cessation, Chest 2020; 158 (3); 1060-8. doi: 10.1016/j.chest.2020.03.026
Nelson G, Girdler-Brown B, Ndlovu N, Murray J. Three decades of silicosis: disease trends at autopsy in South African gold miners. Environ Health Perspect. 2010; 118 (3): 421-6. doi: 10.1289/ehp.0900918
Bukovitz B, Meiman J, Anderson H, Brooks EG. Silicosis: Diagnosis and Medicolegal Implications. J Forensic Sci 2019; 64(5): 1389-98. doi: 10.1111/1556-4029.14048
Romero M, Varona M, Ibañez-Pinilla M, Briceño L. Prevalence of pneumoconiosis and spirometric findings in underground mining workers in Cundinamarca, Colombia. Rev. Fac. Med. 2019; 67 (4): 393-8. https://doi.org/10.15446/revfacmed.v67n4.72201
Fan Y, Xu W, Wang Y, Wang Y, Shiwen Yu S, Qiao Ye Q. Association of occupational dust exposure with combined chronic obstructive pulmonary disease and pneumoconiosis:a cross-sectional study in China. BMJ Open 2020; 10:e038874. doi: 10.1136/bmjopen-2020-038874
Koskinen H. Symptoms and clinical findings in patients with silicosis. Scand J Work Environ Health 1985; 11(2): 101-6. doi: 10.5271/sjweh.2247.
Talini D, Paggiaro PL, Falaschi F, Battolla L, Carrara M, Petrozzino M, et al. Chestradiography and high resolution computed tomography in the evaluation of workers exposed to silica dust: Relation with functional findings. Occup Environ Med 1995; 52: 262-7. doi: 10.1136/oem.52.4.262.
Preisser A, Schlemmer K, Herold R, Laqmani A, Terschüren C, Harth V. Relations between vital capacity, CO diffusion capacity and computed tomographic findings of former asbestos-exposed patients: a cross-sectional study. J Occup Med Toxicol 2020 Jul 1; 15:21. doi: 10.1186/s12995-020-00272-1
Blanco-Pérez J, Arnalich-Montiel V, Salgado-Barreira A. The 6-Minute Walk Test as a Tool for Determining Exercise Capacity and Prognosis in Patients with Silicosis. Arch Bronconeumol 2019; 55 (2): 88-92. doi: 10.1016/j.arbres.2018.07.004
Sauni R, Oksa P, Lehtimäki L, Toivio P, Palmroos P, Nieminen R, et al. Increased alveolar nitric oxide and systemic inflammation markers in silica-exposed workers. Occup. Environ. Med. 2012, 69, 256-260. doi: 10.1136/oemed-2011-100347
Ferrante P. Asbestosis and silicosis hospitalizations in Italy (2001-2015): results from the National Hospital Discharge Registry. Eur J Public Health 2019; 1;29 (5): 876-82. doi: 10.1093/eurpub/ckz003.
Ehrlich R, Akugizibwe P, Siegfried N, Nandi Siegfried N, Rees D. The association between silica exposure, silicosis and tuberculosis: a systematic review andmeta-analysis. BMC Public Health. 2021; 21: 953. doi:10.1186/s12889-021-10711-1
Pérez D, Oviedo J, Gill DS. Paracoccidioidomicosis: características clínicas de 94 casos. Rev Amer Med Respiratoria 2014; 1(20): 20-7. http://www.scielo.org.ar/pdf/ramer/v14n1/v14n1a05.pdf
Iossifova Y, Bailey R, Wood J, Kreiss K. Concurrent silicosis and pulmonary mycosis at death. Emerg Infect Dis. 2010 Feb; 16(2): 318-20. doi: 10.3201/eid1602.090824.
Chen GX, Burnett CA, Cameron LL, Alterman T, Lalich NR, Tanaka S, et al. Tuberculosis mortality and silica exposure: a case-control study based on a national mortality database for the years 1983-1992. Int J Occup Environ Health. 1997;3: 163-70.
Murray J, Reid G, Kielkoxski D, de Beer M. Cor pulmonale and silicosis: a necropsy based case-control study.Br J Ind Med 1993 Jun; 50(6): 544-8. doi: 10.1136/oem.50.6.544.
Esfahani M, Bashirian S, Mehri F Khazaei S. Association between Silica Exposure and Cardiovascular Disease Mortality: A Meta-Analysis. J Tehran Heart Cent. 2020; 15(4): 151-7. doi: 10.18502/jthc.v15i4.5940
Crowley LE, Herbert R, Moline JM, Wallenstein S, Shukla G, Schechter C, et al. “Sarcoid like" granulomatous pulmonary disease inWorld Trade Center disaster responders. Am J Ind Med. 2011; 54:175-84. doi: 10.1002/ajim.20924.
Webber MP, Moir W, Crowson CS, Cohen HW, Zeig-Owens R, Hall CB, et al. Post-September 11, 2001, incidence of systemic autoimmune diseases in World Trade Center-exposed firefightersand emergency medical service workers. Mayo Clin Proc. 2016; 91:23-32. doi: 10.1016/j.mayocp.2015.09.019.
Shtraichman O, Blanc PD, Ollech JE, Fridel L, Fuks L, Fireman E, et al. Outbreak of autoimmune disease in silicosis linked to artificial stone. Occup Med (Lond) 2015; 65 (6): 444-50. doi: 10.1093/occmed/kqv073
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Arsenic, Metals, Fibres and Dusts. Lyon (FR): International Agency for Research on Cancer; 2012. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , No. 100C.) Silica dust, crystalline, in the form of quartz or cristobalite. Acceso el 29/10/2022. https://www.ncbi.nlm.nih.gov/books/NBK304370/
Holanda MA, Holanda MA, Martins MP, Felismino PH, Pinheiro VG. Alcǎntara Holanda M, Alcǎntara Holanda M, Felismino PH, Ferreira Pinheiro VG. Silicosis in brazilian pit diggers: Relationship between dust exposure and radiologic findings. Am J Ind Med 1995; 27(3): 367-78. doi: 10.1002/ajim.4700270306
Yılmaz-Çankaya B, Karaman A, Albez FS, Polat G, Alper F, Akgün M. The association of silicosis severity with pectoralis major muscle and subcutaneous fat volumes and the pulmonary artery/aorta ratio evaluated by CT. Diagn Interv Radiol. 2021; 27(1): 37-41. doi: 10.5152/dir.2020.19534
Martínez-González C, Prieto-González A, García Alfonso L, Lonighi SS, Maqueda J. Silicosis en trabajadores con conglomerados artificiales de cuarzo. Arch bronconeumol 2019; 55(9); 459-64. doi: 10.1016/j.arbres.2019.01.017
Holanda MA, Peixoto AC, Holanda AA, Gomes do Monte C, Bezerra Leite E, Luiz Ximenes L Junior, et al. Silicose em cavadores de poços da região de Ibiapaba (CE): da descoberta ao controle. J Pneumol 1999; 25 (1): 1-11.
McKimmie T, Szurmak J. ‘Beyond grey literature: how grey questions can drive research’, Journal of Agriculture and Food Information 2002; 4(2): 71-9. doi.org/10.1300/J108v04n02_06
Cleo Pappas C, Williams I. Grey Literature: Its Emerging Importance, Journal of Hospital Librarianship 2011: 11(3): 228-34. 10.1080/15323269.2011.587100
