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Memorias del Instituto de Investigaciones en Ciencias de la Salud (Mem. Inst. Investig. Cienc. Salud) is the official publication of the Institute of Research in Health Sciences (IICS) of the National University of Asunción (UNA), Paraguay. It publishes original scientific contributions in clinical medicine, biomedical research, microbiology, molecular biology, dentistry, nursing, nutrition, public health, health biotechnology, genetics, biochemistry, and related disciplines. Founded in 1983, the journal adopted its current name in 2002 and has been published exclusively online since 2015, incorporating XML article dissemination as of 2024. Since 2023, it operates under a continuous publication model. The journal accepts manuscripts in Spanish and English as original research articles, reviews, case studies, and brief communications. All content is available in open access, free of charge for authors and readers, under the Creative Commons Attribution 4.0 International License, in accordance with the Budapest Open Access Initiative (BOAI). It is indexed in BVS, SciELO Paraguay, HINARI, LILACS, DOAJ, Latindex, MIAR, Dialnet, CiteFactor, Google Scholar, LivRe, BASE, EBSCO, and Web of Science – SciELO Citation Index. The journal is funded by IICS-UNA, supports the OAI-PMH protocol for metadata harvesting, and uses the LOCKSS system for digital preservation of its contents.

 
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Manuscripts submitted to Memorias del Instituto de Investigaciones en Ciencias de la Salud undergo a double-blind peer review process, in which the identities of both authors and reviewers remain anonymous throughout the evaluation. Each manuscript is assessed by a minimum of two external reviewers with expertise in the relevant subject area, who are given a period of 30 days to submit their evaluation. Reviewers assess the originality, methodological rigor, scientific relevance, and clarity of presentation of each work. Based on the reviewers' reports, the Editorial Committee decides whether to accept, request revisions, or reject the manuscript, and communicates the decision to the authors as promptly as possible. This process ensures impartiality, transparency, and the scientific quality of published articles.

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The Institute of Research in Health Sciences (IICS) of the National University of Asunción (UNA) invites researchers, academics, and health professionals to submit their manuscripts for consideration in the 2026 Volume of Memorias del Instituto de Investigaciones en Ciencias de la Salud (Mem. Inst. Investig. Cienc. Salud). The journal accepts original and unpublished contributions in Spanish as original research articles, review articles, case studies, and brief communications, in the areas of clinical medicine, biomedical research, microbiology, molecular biology, dentistry, nursing, nutrition, public health, health biotechnology, genetics, biochemistry, and related disciplines. The call for submissions is open and ongoing, and manuscripts may be submitted at any time of the year through the journal's online submission system. All received manuscripts undergo double-blind peer review. The journal is open access, with no charges for authors or readers. For further information on submission guidelines, please refer to the author instructions available on the journal's website.

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Etiology of leukocytosis in patients hospitalized at the General Hospital of Luque, Paraguay, between January and September 2024

Authors

DOI:

https://doi.org/10.18004/mem.iics/1812-9528/2025.e23122508

Keywords:

infections, chronic diseases, Paraguay

Abstract

This study, with a quantitative approach and cross-sectional observational analytical design, aimed to identify and analyze the main causes of leukocytosis in patients admitted to the Internal Medicine Department of the Luque General Hospital (Paraguay) between January and September 2024, considering predisposing factors and their impact on clinical diagnosis. A total of 1,296 adult patients with laboratory-confirmed leukocytosis were included, excluding those with chronic hematological diseases or undergoing immunosuppressive treatment. Data were collected through medical record review and analyzed statistically. The results showed that the most frequent causes of leukocytosis were respiratory infections (pneumonia), skin and soft tissue infections, chronic diseases such as chronic kidney disease (CKD), cerebrovascular accidents (CVA), and heart disease, with a high incidence observed in elderly patients and those with comorbidities. Furthermore, a significant increase in cases was identified during the months of August and September, possibly linked to seasonal factors. These findings underscore the need for clinical surveillance and prevention strategies focused on patients at higher risk.

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References

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Tabla 1. Diagnósticos más frecuentes asociados a leucocitosis (n = 1.296)

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Published

2025-12-30

Issue

Section

Original Articles

How to Cite

Do Monte Silva, E. R., Acosta Zayas, M. C. ., Duarte Benítez, F. R., Ortellado Gonzalez, A., Matto Ayala, B. R., & Velázquez Zaracho, R. C. (2025). Etiology of leukocytosis in patients hospitalized at the General Hospital of Luque, Paraguay, between January and September 2024. Memorias Del Instituto De Investigaciones En Ciencias De La Salud, 23(01). https://doi.org/10.18004/mem.iics/1812-9528/2025.e23122508