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Memorias del Instituto de Investigaciones en Ciencias de la Salud (Mem. Inst. Investig. Cienc. Salud) is the official publication of the Institute of Research in Health Sciences (IICS) of the National University of Asunción (UNA), Paraguay. It publishes original scientific contributions in clinical medicine, biomedical research, microbiology, molecular biology, dentistry, nursing, nutrition, public health, health biotechnology, genetics, biochemistry, and related disciplines. Founded in 1983, the journal adopted its current name in 2002 and has been published exclusively online since 2015, incorporating XML article dissemination as of 2024. Since 2023, it operates under a continuous publication model. The journal accepts manuscripts in Spanish and English as original research articles, reviews, case studies, and brief communications. All content is available in open access, free of charge for authors and readers, under the Creative Commons Attribution 4.0 International License, in accordance with the Budapest Open Access Initiative (BOAI). It is indexed in BVS, SciELO Paraguay, HINARI, LILACS, DOAJ, Latindex, MIAR, Dialnet, CiteFactor, Google Scholar, LivRe, BASE, EBSCO, and Web of Science – SciELO Citation Index. The journal is funded by IICS-UNA, supports the OAI-PMH protocol for metadata harvesting, and uses the LOCKSS system for digital preservation of its contents.

 
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Manuscripts submitted to Memorias del Instituto de Investigaciones en Ciencias de la Salud undergo a double-blind peer review process, in which the identities of both authors and reviewers remain anonymous throughout the evaluation. Each manuscript is assessed by a minimum of two external reviewers with expertise in the relevant subject area, who are given a period of 30 days to submit their evaluation. Reviewers assess the originality, methodological rigor, scientific relevance, and clarity of presentation of each work. Based on the reviewers' reports, the Editorial Committee decides whether to accept, request revisions, or reject the manuscript, and communicates the decision to the authors as promptly as possible. This process ensures impartiality, transparency, and the scientific quality of published articles.

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The Institute of Research in Health Sciences (IICS) of the National University of Asunción (UNA) invites researchers, academics, and health professionals to submit their manuscripts for consideration in the 2026 Volume of Memorias del Instituto de Investigaciones en Ciencias de la Salud (Mem. Inst. Investig. Cienc. Salud). The journal accepts original and unpublished contributions in Spanish as original research articles, review articles, case studies, and brief communications, in the areas of clinical medicine, biomedical research, microbiology, molecular biology, dentistry, nursing, nutrition, public health, health biotechnology, genetics, biochemistry, and related disciplines. The call for submissions is open and ongoing, and manuscripts may be submitted at any time of the year through the journal's online submission system. All received manuscripts undergo double-blind peer review. The journal is open access, with no charges for authors or readers. For further information on submission guidelines, please refer to the author instructions available on the journal's website.

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Primer reporte de queratitis por Nocardia brasiliensis en Paraguay

Authors

  • Ramona Sanabria IICS-UNA
  • E Escurra Hospital de Clínicas. Universidad Nacional de Asunción Author
  • Norma Fariña IICS-UNA Author
  • Florentina Laspina IICS-UNA Author
  • Margarita Samudio IICS-UNA Author
  • D Cibilis Hospital de Clínicas. Universidad Nacional de Asunción Author
  • I Santacruz IICS-UNA Author

Keywords:

queratitis, Gentamicina, N. brasiliensis

Abstract

La queratitis producida por Nocardia spp es raramente reportada en el mundo por lo que su incidencia no está aún bien establecida. En el presente estudio se reporta el primer caso de queratitis por Nocardia brasiliensis en Paraguay en un paciente de sexo masculino, de profesión jardinero, procedente de la ciudad de Asunción, y con antecedente de traumatismo con rama de arbusto quince días antes de la consulta. El paciente acude al servicio de Oftalmología del Hospital de Clínicas, debido a ojo rojo, agudeza visual disminuida e intenso dolor en el ojo izquierdo con una semana de evolución. Se realiza tratamiento con la aplicación de colirio reforzado de gentamicina 14 mg/ml y cefazolina 50 mg/ml, cada una hora, observándose mejoría de los síntomas y de la agudeza visual a los 10 días de seguimiento. La evolución clínica en queratitis a Nocardia spp es buena siempre que el diagnóstico etiológico se realice sin demora y correctamente. Es muy importante diferenciar los bordes de las lesiones de la úlcera de córnea producidas por hongos, bacterias filamentosas y otras bacterias, además considerar la presencia de lesiones satélites.

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References

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Brown-Elliot BA, Brown JM, Conville PS, Wallace RJ. Clinical and laboratory features of the Nocardia spp.based on current molecular taxonomy. Clin Microbiol Rev 2006;19(2):259-2.

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Kiska D, Hicks K, Pettit D. Identification of medically relevant Nocardia species with an abbreviated battery of test. J Clin Microbiol 2002; 40(4): 1346–51.

Hoffman PM, Poon A, Snibson GR. Nocardia keratitis in a contact lens wearer. Arch Ophthalmol 2005; 123(12):1759.

Eggink C, Wesseling P, Boiron P, Meis J. Severe keratitis due to Nocardia farcinica. J. Clin. Microbiol 1997;35(4):999-1001.

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Published

2012-06-01

Issue

Section

Case report

How to Cite

Sanabria, R., Escurra, E., Fariña, N., Laspina, F. ., Samudio, M., Cibilis, D., & Santacruz, I. (2012). Primer reporte de queratitis por Nocardia brasiliensis en Paraguay. Memorias Del Instituto De Investigaciones En Ciencias De La Salud, 10(1). https://revistascientificas.una.py/index.php/RIIC/article/view/1724