Surgical - pathologic concordance in the diagnosis of the acute apendicitis

Authors

  • Dr. Helmut Alfredo Segovia Lohse Dr. Helmut Alfredo Segovia Lohse Segunda Cátedra de Clínica Quirúrgica. Facultad de Ciencias Médicas. Universidad Nacional de Asunción.
  • SJ Figueredo Thiel Cátedra de Anatomía Patológica Facultad de Ciencias Médicas. Universidad Nacional de Asunción

DOI:

https://doi.org/10.18004/

Keywords:

Appendicitis, Appendectomy, Concordance, Diagnostic errors, Paraguay

Abstract

Background: It is necessary to make a correct classification of acute appendicitis due to the different treatment according to the stage of the disease. Several studies have analyzed the surgical and pathologic concordance with varying results. The objective of this study is to determine the correlation between the surgical diagnosis made by the surgeon and the pathological report made by the pathologist. Methods: Observational analytic, inter-observer agreement study, of 266 of patients older than 15 years with a diagnosis of acute appendicitis operated in 2008-2009. Descriptive statistics were used for demographics, and nonparametric statistics (kappa index) to analyze the correlation between the surgical diagnosis and pathology report. Results: 266 patients with an average age of 31 (± 13, 15-86) and male/female ratio of approximately 3:2. The diagnosis of acute appendicitis was performed in 98% and 94% by surgeons and pathologists respectively, with a kappa index of 0.3466 (SE 0.1705, 0.0104-0.6788, 95%). Surgeons diagnosed as such only 24% of the appendix without inflammation confirmed by pathology. Categorizing acute appendicitis as congestive, phlegmonous and gangrenous/perforated a kappa index was obtained of 0.2235 (SE 0.0487, 0.1281-0.3189, 95%). Negative appendectomy was 6%. Conclusions: The surgicalpathologic concordance was poor. Surgeons have an inadequate ability to exactly classify non inflamed appendix. The negative appendectomy rate was low.

References

1. Lagattolla N. Acute appendicitis. In Lattimer CR, Wilson NM, Lagattolla NRF. Key Topics in

General Surgery. 2nd ed. Oxford: Bios, 2002.

2. Rebollar González RC, García Alvarez J, Trejo Téllez R. Apendicitis aguda: Revisión de la

literatura. Rev Hosp Jua Mex 2009;76(4):210-216.

3. Morris J, Barker DJ, Nelson M. Diet, infection, and acute appendicitis in Britain and Ireland. J

Epidemiol Community Health. 1987 Mar;41(1):44-9.

4. Turner JR. The Gastrointestinal Tract. In Kumar V, Abbas A, Fausto N, Aster J: Robbins and

Cotran Pathologic Basis of Disease, Professional Edition. 8th ed. Philadelphia: Saunders

Elsiever, 2009.

5. Sarosi GA, Turnage RH. Appendicitis. In Feldman M, Friedman LS, Brandt LJ. Sleisenger &

Fordtran's Gastrointestinal and Liver Disease. 8th ed. Philadelphia: Saunders Elsiever, 2006.

6. Kulikoff B, Vargas F, Rodríguez C. Correlación clínico patológica en la apendicitis aguda

pediátrica: revisión de 782 casos. Rev Ped. Elec [en línea] 2009 Dic;6(3):121.

7. Raja AS, Wright C, Sodickson AD, Zane RD, Schiff GD, Hanson R, Baeyens PF, Khorasani R.

Negative appendectomy rate in the era of CT: an 18-year perspective. Radiology. 2010

Aug;256(2):460-5. Epub 2010 Jun 7.

8. Chamisa I. A clinicopathological review of 324 appendices removed for acute appendicitis in

Durban, South Africa: a retrospective analysis. Ann R Coll Surg Engl. 2009 Nov;91(8):688-92.

9. Rodriguez-Herrera G. Revisión de casos operados con diagnóstico clínico de apéndicitis

aguda en pacientes. Acta Méd Costarric. 2003 Jun;45(2):62-7.

10. Schumpelick V, Dreuw B, Ophoff K, Prescher A. Appendix and cecum. Embryology, anatomy,

and surgical applications. Surg Clin North Am. 2000 Feb;80(1):295-318.

11. Flores-Nava G, Jamaica-Balderas ML, Landa-García RA, Parraguirre-Martínez S, Lavalle-

Villalobos A. Apendicitis en la etapa pediátrica: correlación clínico-patológica. Bol Med Hosp

Infant Mex 2005;62(3):195-201.

12. Soto-López A, Águila-Melero O, Reyes-Corcho A, Consuegra-Díaz JE, Gómez-Baute R.

Eficiencia diagnóstica en la apendicitis aguda. Cir Ciruj 2003;71:204-209

13. Guzmán-Valdivia Gómez G. Una clasificación útil en apendicitis aguda. Rev Gastroenterol

Mex 2003;68(4):261-265.

14. Alamili M, Gögenur I, Rosenberg J. Oral antibiotics for perforated appendicitis is not

recommended. Dan Med Bull. 2010 Sep;57(9):A4177.

15. Bliss D, Mckee J, Cho D, Krishnaswami S, Zallen G, Harrison M, Silen M. Discordance of the

pediatric surgeon's intraoperative assessment of pediatric appendicitis with the pathologists

report. J Pediatr Surg. 2010 Jul;45(7):1398-403.

16. Geryk B, Kubíková E, Jakubovský J. [Clinical and histopathologic picture of acute appendicitis

in children]. [Article in Slovak]. Rozhl Chir. 2000 May;79(5):211-4.

17. Macias-Magadan M, Cordero-Olivares A, Fonseca I. Apendicitis: Incidencia y correlación

clínico patológica Experiencia de 5 años. Rev Mex Cir Pediatr 2009;16(4):170-5.

18. Marudanayagam R, Williams GT, Rees BI. Review of the pathological results of 2660

appendicectomy specimens. J Gastroenterol. 2006 Aug;41(8):745-9.

19. Grunewald B, Keating J. Should the 'normal' appendix be removed at operation for

appendicitis? J R Coll Surg Edinb. 1993 Jun;38(3):158-60.

20. Ojo OS, Udeh SC, Odesanmi WO. Review of the histopathological findings in appendices

removed for acute appendicitis in Nigerians. J R Coll Surg Edinb. 1991 Aug;36(4):245-8.

21. Astroza G, Cortés C, Pizarro H, Umaña M, Bravo M, Casas R. Diagnóstico clínico en

apendicitis aguda: una evaluación prospectiva. Rev Chil Cir 2005 Ago;57(4):337-9.

22. Hussain A, Mahmood H, Singhal T, Balakrishnan S, El-Hasani S. What is positive

appendicitis? A new answer to an old question. Clinical, macroscopical and microscopical

findings in 200 consecutive appendectomies. Singapore Med J 2009; 50(12):1145.

Downloads

Published

2026-11-05

How to Cite

Surgical - pathologic concordance in the diagnosis of the acute apendicitis. (2026). Anales of the Faculty of Medical Sciences, 45(1), 35-43. https://doi.org/10.18004/