PENILE LEPROMATOUS LEPROSY IN A PATIENT WITH CHAGAS DISEASE.A CASE REPORT

Authors

  • Antonio Cubilla Profesor en Patología. Facultad de Ciencias Médicas de la Universidad Nacional de Asunción e Instituto de Patología e Investigación. Paraguay
  • P Zarza Estudiante de 6to curso. Facultad de Ciencias Médicas de la Universidad Nacional de Asunción. Paraguay
  • C Hong Estudiante de 6to curso. University High School. Irvine. California
  • B Park Estudiante de 5to curso. Woodbridge High School. Irvine. California
  • G Molinas Residente de Neumología. Instituto Nacional de Enfermedades Respiratorias. Asunción. Paraguay
  • MA Gonzalez Facultad de Ciencias Médicas de la Universidad Nacional de Asunción e Instituto de Patología e Investigación. Paraguay
  • DF Sánchez Facultad de Ciencias Médicas de la Universidad Nacional de Asunción e Instituto de Patología e Investigación. Paraguay
  • G Mendoza de Sánchez Dermatopatóloga

DOI:

https://doi.org/10.18004/anales/2016.049(02)69-077

Keywords:

Leprosy, Lepromatous, Chagas Disease, Phimosis, Paraguay

Abstract

We are presenting a 52-year-old patient with phimosis due a tumor like mass, which on pathological evaluation was diagnosed as lepromatous leprosy. The patient had a history of Hansen’s disease involving the skin, the larynx and the bronchial tree. Before a circumcision, a physical examination revealed in addition to the lepromatous changes the presence of megaesophagus secondary to stenosis of the distal portion. Laboratory analysis for Tripanosomacruzii using ELISA technique was positive for Chagas Disease. We could find only one previous report of lepromatous leprosy affecting the foreskin. The coexistence of leprosy and myocardial Chagas disease is unusual but well known in reports from Brazil and India. However, this is, to our knowledge, the first case reported of an association of lepromatous leprosy and chagasicmegaesophagus in a patient with phimosis.

References

1. Anish SA. The relationship between surface temperature and dermal invasion in lepromatous leprosy.Int J Lepr Other Mycobact Dis. 1971;39(4); 848-51

2. Indira D, Kaur I, Sharma VK, Das A. Palmoplantar lesions in leprosy. Indian J Lepr 1999;71(2);167-72

3. Jopling WH, McDougall AC. Handbook of leprosy, 5ed, New Delhi: CBS Publications 1996:10-49pp

4. Fox H, Knott J. Leprous nodules on male genitalia. Int J Lepr, 1934;2;445-46

5. Ghorpade A, Ramanan C. Primary penile tuberculoid leprosy. Indian J Lepr2000;72;499-500

6. Shaw N, Ebenezer G, Rao S. Leprosy lesion on the prepuce of the male genitalia: a case report. Lepr Rev. 2002;73;276-78

7. Kumar B, Kaur I, Rai R, Mandaal SK, Sharma VK. Involvement of male genitalia in leprosy.Lepr Rev 2001;72(1);70-7

8. Grabstald H, Lawrence S. Genitourinary lesions in leprosy with special reference to the problem of atrophy of the testes. JAMA, 1952 149(14); 1287-91.

9. Arora SK, Mukhija RD, Mohan L, Girdhar M. A study of cutaneous lesions on male external genitalia.Indian J Lepr 1989;61(2);222-24

10. Desikan KV, Iyer CG. Histioid variety of lepromatous leprosy: A histopathologic study. Int J Lepr Other Mycobact Dis. 1972;40;149-56

11. Mukhopadhyay AK. Primary involvement of penile skin in lepromatous leprosy.Indian J Lepr2005; 77(4); 317-21

12. Kaliyadan F, Dharmaratnam A, Cyriac M. Histioid leprosy with penile shaft lesions. Indian Dermatology Online Journal. 2012;3(1);68-70

13. Badge S, Gosavi A, Ramteerthkar N, Sulhyan K. Lepromatous leprosy of the prepuce- A case report. Journal of Krishna Institute of Medical Sciences University. 2013; 2(1);117-19

14. Global Leprosy Situation, World Health Organization WklyEpidemiol Rec. 2013; 33;333-40

15. Trindade M, Carvalho N, Belfort E, Pagliari C, Gakiya E, Sakai-Valente N, Benard G, Shikanai-Yasuda M. A patient with Erythema NodosusLeprosum and ChagasCardiopathy: Challenges in patient management and review of the literature. The American Journal of Tropical Medicine and Hygiene. 2011;84(6);973-77

16. Bottasso OA, Morini JC. Electrocardiographic alterations in lepromatous leprosy patients with concomitant Trypanosomacruzi infection.Int. J Lepr. 1993;61;468-71

17. Oertell J, Caballero C, Iglesias M, Chaux A, Amat L, Ayala E, Rodriguez I, Velaquez EF, Barreto JE, Ayala G, Cubilla AL. Differentiated precursor lesions and low-grade variants of squamous cell carcinoma are frequent findings in foreskins of patients from a region of high penile cancer incidence. Histopathology. 2011;58(6);925-33

18. Kar BR, Ebenezer G, Job CK. Penile tuberculoid leprosy in five year old boy. Indian J DermatolVenereolLeprol. 2005;71(2);125-27

19. Diniz O. Lepra e doença de Chagas. Arq Min Leprol 1948;8;155-69

20. Dias JCP, Cunha DA. Hansensíase e doença de Chagas. Estudosreahzados no Sanatório São Francisco de Assis, emBabuí, Minas Gerais. Rev Soc Med Trop. 1970;4;31-43

21. Mathur SN, Itigi A, Krishnaveni A, Rao PD. Congestive heart failure in two patients with lepromatous leprosy. Lepr India. 1976;48;75-80

22. Lima MA, Rodrigues-Jr V, Silva-Vergara ML, Nomelini MB, Paim N, Santos TA, Santos VM. Hanseníasevirchowianaemcardiopatachagásico: relato de necropsia. Relato de caso. Rev Soc Bras Med Trop. 1998;31;385-90.

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Published

2026-10-28

How to Cite

PENILE LEPROMATOUS LEPROSY IN A PATIENT WITH CHAGAS DISEASE.A CASE REPORT. (2026). Anales of the Faculty of Medical Sciences, 49(2), 69-77. https://doi.org/10.18004/anales/2016.049(02)69-077