Enfermedad celiaca silente en pacientes adultos con enfermedades tiroideas autoinmunes

Raúl Emilio Real; José Antonio José Antonio; Nelson Rodrigo González

doi:10.18004/anales/2020.053.01.71-080

Authors

Raúl Emilio Real Universidad Nacional de Itapúa, Facultad de Medicina, Postgrado en Medicina Interna. Encarnación, Paraguay.
José Antonio José Antonio Universidad Nacional de Itapúa, Facultad de Medicina, Postgrado en Medicina Interna. Encarnación, Paraguay.
Nelson Rodrigo González Universidad Nacional de Itapúa, Facultad de Medicina, Postgrado en Medicina Interna. Encarnación, Paraguay.

DOI:

https://doi.org/10.18004/anales/2020.053.01.71-080

Keywords:

Celiac disease, Anti-transglutaminase antibody, Hashimoto’s thyroiditis, Graves’ disease, Paraguay

Abstract

Introduction: celiac disease may be asymptomatically associated with autoimmune thyroiditis. Objective: to determine the presence of silent celiac disease in patients with autoimmune thyroiditis.Methodology: we carried out a observational, prospective, multicenter study in adult patients with Hashimoto’s thyroiditis and Graves’ disease from three hospitals in Paraguay in the years 2018-2019. The presence of IgA antitransglutaminase and serum IgA antibodies was determined in those who agreed to participate in the study. Demographic and clinical variables were also measured. The study was approved by the Ethics Committee of the National University of Itapúa. Results: 87 patients were contacted, but the final sample was established with 22 subjects. The mean age was 50 years, with a predominance of the female (77%). Antibodies to celiac disease were detected in 3 cases (13%) and all were confirmed with a duodenal biopsy. Conclusions: the frequency of silent celiac disease in patients with Hashimoto’s thyroiditis and
Graves’ disease was 13%.

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