Malignant syphilis: report of 2 cases in patients without AIDS

Authors

Keywords:

syphilis, malignant syphilis, diagnosis of syphilis

Abstract

Syphilis is a multifaceted disease that always requires differential diagnoses. A rare form of
secondary syphilis is the so-called malignant syphilis characterized by necrotic ulcerated lesions
covered by thick crusts with a rupioid or ostraceous appearance. Currently observed mainly in
patients infected with the human immunodeficiency virus, but it was previously described in
other debilitating situations such as alcoholism, y malnutrition.
Eventually it can be seen in immunocompetent patients like the 2 cases we present.

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References

Fustá X, Morgado D, Barreiro A, Capurro A, Manzardo C, Alsina M y Miembros del Grupo de Trabajo de Infecciones de Transmisión Sexual del Hospital Clinic de Barcelona. Sífilis maligna, una presentación de sífilis a tener en cuenta. Actas Dermosifiliogr. 2019; 110 (3): 232-237 https:/doi.org/10.1016/ j.ad.2018.02.024.

Mohan G, Ali R, Isache C, Sharma R, Perniciaro C. Malignant syphilis: Ostraceous, ulceronecrotic lesions in a patient with human immunodeficiency virus. Dermatol Online J. 2017; 23: 1-3

Garbarino M, Trila C, Heffner L, Cantón M, Quadrana F, Zylberman M. Sífilis maligna en paciente con infección por el virus de la inmunodeficiencia humana. Medicina (Buenos Aires) 2020; 80: 714-717

Calderón L, Arguedas Ortiz J. Ulloa M. Sífilis maligna como manifestación clínica atípica de sífilis secundaria. Revista Médica Sinergia 2023;8(6). https://doi.org/10.31434/rms.v8i6.1001

Jia-Qi Chen, Yue-Lan Cao, Xiao-Yong Man. Malignant syphilis in a Young woman: A case report. Journal of International Medical Research 2022; 50 (10): 1-5 DOI: 10.1177/03000605221131368.

García F, Fernández V, Sánchez D, Toribio J. Malignant syphilis in an inmunocompetent patient. Actas Derosifiliogr.2012; 103: 437-9

De Unamuno B, Sánchez R, Carazo J, de Miquel V. Malignant syphilis with ocular involvement in an immunocompetent patient. Int J Dermatol.2014; 53: 258 -60

Witkowski J, Parish L. The great imitador: Malignant syphilis with hepatitis. Clin Dermatol.2002; 20: 156-63

Wibisono O, Idrus I, Djawad K. Sífilis maligna: revisión sistemática de los casos publicados entre los años 2014-2018. Actas Dermosifiliogr. 2021;112:725-734 https:/doi.org/10.1016/ j.ad.2021.02.011.

Fisher D, Chang L, Tuffanelli D. Malignant syphilis. Presentation of a case and review of the literature. Arch Dermatol 1969; 90: 70-3

Pérez C, Londoño A, Londoño A, Peña E. Sífilis maligna: reporte de 2 casos y revisión de la literatura. Piel (Barc) 2017: 32 (9): 585-596 https://dx.doi.org/10. 1016/j.piel. 2017.04.013.

Figura 3. Caso 1. Anatomía patológica. Coloración de Warthin-Starry. Elementos espiralados tipo espiroquetas

Published

2023-12-11

How to Cite

Aldama Caballero, A., Elli, M. M., & Montoya, C. (2023). Malignant syphilis: report of 2 cases in patients without AIDS. Anales of the Faculty of Medical Sciences, 56(3), 84–88. Retrieved from https://revistascientificas.una.py/index.php/RP/article/view/3916