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Memorias del Instituto de Investigaciones en Ciencias de la Salud (Mem. Inst. Investig. Cienc. Salud) is the official publication of the Institute of Research in Health Sciences (IICS) of the National University of Asunción (UNA), Paraguay. It publishes original scientific contributions in clinical medicine, biomedical research, microbiology, molecular biology, dentistry, nursing, nutrition, public health, health biotechnology, genetics, biochemistry, and related disciplines. Founded in 1983, the journal adopted its current name in 2002 and has been published exclusively online since 2015, incorporating XML article dissemination as of 2024. Since 2023, it operates under a continuous publication model. The journal accepts manuscripts in Spanish and English as original research articles, reviews, case studies, and brief communications. All content is available in open access, free of charge for authors and readers, under the Creative Commons Attribution 4.0 International License, in accordance with the Budapest Open Access Initiative (BOAI). It is indexed in BVS, SciELO Paraguay, HINARI, LILACS, DOAJ, Latindex, MIAR, Dialnet, CiteFactor, Google Scholar, LivRe, BASE, EBSCO, and Web of Science – SciELO Citation Index. The journal is funded by IICS-UNA, supports the OAI-PMH protocol for metadata harvesting, and uses the LOCKSS system for digital preservation of its contents.

 
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Manuscripts submitted to Memorias del Instituto de Investigaciones en Ciencias de la Salud undergo a double-blind peer review process, in which the identities of both authors and reviewers remain anonymous throughout the evaluation. Each manuscript is assessed by a minimum of two external reviewers with expertise in the relevant subject area, who are given a period of 30 days to submit their evaluation. Reviewers assess the originality, methodological rigor, scientific relevance, and clarity of presentation of each work. Based on the reviewers' reports, the Editorial Committee decides whether to accept, request revisions, or reject the manuscript, and communicates the decision to the authors as promptly as possible. This process ensures impartiality, transparency, and the scientific quality of published articles.

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The Institute of Research in Health Sciences (IICS) of the National University of Asunción (UNA) invites researchers, academics, and health professionals to submit their manuscripts for consideration in the 2026 Volume of Memorias del Instituto de Investigaciones en Ciencias de la Salud (Mem. Inst. Investig. Cienc. Salud). The journal accepts original and unpublished contributions in Spanish as original research articles, review articles, case studies, and brief communications, in the areas of clinical medicine, biomedical research, microbiology, molecular biology, dentistry, nursing, nutrition, public health, health biotechnology, genetics, biochemistry, and related disciplines. The call for submissions is open and ongoing, and manuscripts may be submitted at any time of the year through the journal's online submission system. All received manuscripts undergo double-blind peer review. The journal is open access, with no charges for authors or readers. For further information on submission guidelines, please refer to the author instructions available on the journal's website.

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Correlación entre el aclaramiento de creatinina y la fórmula MDRD-4 en la estimación del filtrado glomerular

Authors

  • Jorge Zenteno
  • Liliana Sosa
  • Margarita Samudio
  • Irene Ruíz
  • Jenny Stanley
  • Patricia Funes

Keywords:

Filtrado glomerular, aclaramiento de creatinina, MDRD-4

Abstract

La creatinina sérica y el aclaramiento de creatinina (ClCr) son los métodos
mayoritariamente empleados como medida del Filtrado Glomerular (FG), procedimientos
no exentos de problemas tanto preanalíticos como analíticos. En los últimos años se viene
proponiendo la utilización de fórmulas predictivas del FG. Buscamos comprobar la
correlación entre el método analítico y el estimado por la ecuación de MDRD-4. Se
estudiaron retrospectivamente 89 pacientes, con un promedio de 51 ± 14 años; 31
varones y 58 mujeres. Aunque la media del FG estimada por la fórmula MDRD-4 fue de
66 ± 28.83 ml/min y la obtenida con la depuración de creatinina fue de 62±30.22ml/min.
(p<0.05); se encontró una correlación positiva entre ambos métodos (r=0,796;
p=0,001). En nuestra población la ecuación MDRD-4 presenta una buena equivalencia con
el ClCr y podría utilizarse para evaluar la función renal en pacientes con riesgo de
desarrollar enfermedad renal crónica (ERC).

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Published

2011-12-01

Issue

Section

Original Articles

How to Cite

Zenteno, J., Sosa, L., Samudio, M., Ruíz, I., Stanley, J., & Funes, P. (2011). Correlación entre el aclaramiento de creatinina y la fórmula MDRD-4 en la estimación del filtrado glomerular. Memorias Del Instituto De Investigaciones En Ciencias De La Salud, 9(2). https://revistascientificas.una.py/index.php/RIIC/article/view/1711

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